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Anyone here familiar with Nipissing for ice fishing? Some buddies of mine want to head up there, but I've heard there's not much left in the lake. Thoughts?

Your best bet would be to go on Ontario Fishing Community and ask there or do a search, lots of members that ice fish up that way.
https://ontariofishingcommunity.com/

We were up there 2 years ago. We rented a bungalow for 3 nights.
Between 4 of us we caught over 70 walleye.
No monsters but between 12 to 18 inches average.
There are lots of outfitters you can rent from.

Hooker